Overview

Evaluating the Effectiveness of Pentoxifylline at Improving Blood Vessel Function in HIV-infected People Not Receiving Antiretroviral Medications

Status:
Completed

Trial end date:
2011-10-01

Target enrollment:

Participant gender:

Summary

People infected with HIV have a greater risk of developing cardiovascular disease than people not infected with HIV. This may be due to increased inflammation brought on by either the HIV infection itself or the use of antiretroviral medications to treat HIV infection. This study will evaluate an anti-inflammatory drug, pentoxifylline, to determine whether it improves blood vessel function and reduces inflammation in people infected with HIV who are not currently receiving antiretroviral medications.

Phase:

Phase 2

Details

Lead Sponsor:

Indiana University

Collaborator:

National Heart, Lung, and Blood Institute (NHLBI)

Treatments:

Pentoxifylline