Overview

Evaluating the Delivery and Effects of THC Vaping Liquids in the Bloodstream

Status:
NOT_YET_RECRUITING
Trial end date:
2028-03-01
Target enrollment:
Participant gender:
Summary
This clinical trial assesses differences in the delivery of THC to the bloodstream depending on whether nicotine vapes are used before or after THC. While there has been much recent publicity about vaping products and concern about their safety considering their increasing use for THC administration, the THC delivery profile associated with THC liquid vaping products in human subjects is currently unknown. Importantly, how the delivery to the bloodstream of THC vaping liquids compare to delivery from smoked cannabis, which is the most used method of cannabis delivery, will serve as an important benchmark for evaluating the delivery and effects of THC vaping products, and their relative safety.
Phase:
EARLY_PHASE1
Details
Lead Sponsor:
Roswell Park Cancer Institute
Collaborator:
National Institute on Drug Abuse (NIDA)
Treatments:
nabiximols
Nicotine
Specimen Handling