Overview

Evaluating Safety and Efficacy of Mesenchymal Stem Cells From Umbilical Cord

Status:
Unknown status
Trial end date:
2020-12-01
Target enrollment:
0
Participant gender:
All
Summary
This study was to evaluate the safety and efficacy of Mesenchymal Stem Cells (MSCs) from umbilical cord in the treatment of 7 knee OA patients by assessing unexplained local and systemic symptoms or death before and at 1, 2, 3, 6 months after the injection.
Phase:
N/A
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Peking University People's Hospital
Criteria
Inclusion Criteria:

① K / L score of 2-3; ② chronic knee pain; ③ no local or systemic infection; ④ without
obvious contraindication of the joint puncture from hematology and biochemical tests; ⑤
informed consent. -

Exclusion Criteria:

① older than 75 years old or less than 18 years old, or without full capacity for civil
conduct; ② HIV, hepatitis virus or syphilis virus infection or their serology is positive;
③ BMI index is greater than 30; ④ congenital or acquired knee deformity; ⑤ pregnant or
lactating women; ⑥ tumor patients; ⑦ immunodeficiency patients; ⑧ intra-articular drug
injection history within 3 months; ⑨ participating in other clinical trials; ⑩ other
patients who researchers believe are not eligible for inclusion such as suffering from
other concomitant diseases. -