Evaluate the Nephrotoxicity by 6% Hydroxyethyl Starch 130/0.4 in Old Patients During Orthopaedic Surgery
Status:
Completed
Trial end date:
2016-01-01
Target enrollment:
Participant gender:
Summary
Hydroxyethyl starch (HES) is commonly used as plasma expander during surgery but may be
nephrotoxic as seen in studies in patients with sepsis. The investigators hypothesized that
the possible nephrotoxicity of 6% HES 130/0.4 could be revealed by measurements of urinary
and plasma neutrophil gelatinase-associated lipocalin and interleukin-18 (IL-18) in old
patients with normal renal function during orthopaedic surgery.
Phase:
N/A
Details
Lead Sponsor:
Yuanyuan Zhang
Collaborators:
Tianjin First Central Hospital Tianjin Union Medical Center