Overview

Evaluate the Effects of Itraconazole and Ciprofloxacin on Single-Dose PK of Pracinostat in Healthy Nonsmoking Subjects

Status:
Completed
Trial end date:
2014-08-01
Target enrollment:
Participant gender:
Summary
This study is designed as a 2-part, open-label study to assess the effect of pracinostat with itraconazole (part 1) and pracinostat with ciprofloxacin (part 2) on the bioavailability of pracinostat. Secondarily to evaluate the safety and tolerability of pracinostat administered with itraconazole or ciprofloxacin.
Phase:
Phase 1
Details
Lead Sponsor:
Helsinn Healthcare SA
MEI Pharma, Inc.
Treatments:
Ciprofloxacin
Hydroxyitraconazole
Itraconazole