Overview

Etoposide Plus Cisplatin Compared With Temozolomide in Patients With Glioblastoma

Status:
Not yet recruiting
Trial end date:
2025-03-01
Target enrollment:
Participant gender:
Summary
Temozolomide provided significant and clinically meaningful benefit in MGMT gene promoter methylation glioblastoma. However, in unmethylated patients, the effect of Temozolomide is limited. The aim of this study is to compare the effect of Etoposide plus Cisplatin and Temozolomide in patients with MGMT gene promoter unmethylation glioblastoma.
Phase:
Phase 2
Details
Lead Sponsor:
Zhongnan Hospital
Treatments:
Etoposide