Etanercept and Methotrexate in Patients to Induce Remission in Early Arthritis (EMPIRE)
Status:
Completed
Trial end date:
2010-11-05
Target enrollment:
Participant gender:
Summary
TRIAL DESIGN
1. Description This is a 18-month, double-blind, randomized, multicentre, outpatient study.
The approximate duration of subject participation will be 18 months and the approximate
total duration of the study will be 42 months. The duration of subject enrollment will
be approximately 24 months.
2. Discussion of Trial Design The study is designed to directly compare the effectiveness
of combination therapy with MTX + ETN versus
3. Principal research question/objective To determine the number of patients in clinical
remission at 12 months of follow-up, as defined as the absence of symptoms and signs of
inflammatory arthritis.