Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder
Status:
Completed
Trial end date:
2008-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to obtain data investigating the safety and efficacy of
eszopiclone for the treatment of post-traumatic stress disorder (PTSD)-related sleep
disturbance and the impact of improved sleep with eszopiclone treatment on neuroendocrine
correlates of PTSD. The investigators hypothesize that eszopiclone will be significantly more
effective than placebo and well tolerated for PTSD-related sleep disturbance, improvement in
sleep will be associated with improvement in overall PTSD symptoms, and patients with
PTSD-related sleep disturbances will have abnormal levels of stress hormones.