Overview

Estriol Treatment in Multiple Sclerosis (MS): Effect on Cognition

Status:
Recruiting
Trial end date:
2022-04-01
Target enrollment:
Participant gender:
Summary
Approximately 50% of people diagnosed with Multiple Sclerosis (MS) will develop problems with cognition. Currently, there are no FDA-approved treatments targeting cognitive function in Multiple Sclerosis. This trial will ascertain whether treatment with an estrogen pill, used in combination with standard MS anti-inflammatory drugs, can improve cognitive testing as compared to treatment with a placebo pill in combination with standard anti-inflammatory drugs in women with MS.
Phase:
Phase 2
Details
Lead Sponsor:
University of California, Los Angeles
Collaborator:
Synthetic Biologics (formerly Adeona Pharmaceuticals)
Treatments:
Norethindrone
Norethindrone Acetate
Progestins