Estimation of the ED95 of Intrathecal Hyperbaric Prilocaine 2% With Sufentanyl for Scheduled Cesarean Delivery
Status:
Completed
Trial end date:
2016-11-01
Target enrollment:
Participant gender:
Summary
Hyperbaric bupivacaine 0.5% associated with opioids is the local anesthetic the most commonly
used for spinal injection in cesarean section. Nevertheless, its use often results in a long
duration of motor nerve block and a haemodynamical instability. Recently developped, the
Prilocaine, with its new 2% hyperbaric formulation, seems to offer a good alternative for
hyperbaric bupivicaine. A first study has determined the ED95 of hyperbaric prilocaine 2% for
intrathecal anesthesia in scheduled cesarean delivery. As opioid adjuvants potentiate the
effect of the local anesthetics while decreasing their dose-related side effects, the aim of
this study is to determine the ED95 of hyperbaric prilocaine 2% with sufentanyl for scheduled
cesarean delivery under spinal anesthesia,by using the Continual Reassessment Method (CRM)