Estimation of Paracetamol in Urine to Assess the Diurnal Variation
Status:
Completed
Trial end date:
2018-01-30
Target enrollment:
Participant gender:
Summary
Paracetamol is an antipyretic drug that is taken orally at different times of the day in same
dose. It is excreted mainly through renal route which may show diurnal variation. In this
study, urinary excretion of paracetamol of 41 healthy men of same age group will be measured
by HPLC after oral administration of 500 mg paracetamol tablet at morning, midday and night.
The measured values will be compared in order to adjust doses of oral paracetamol at
different times of the day.
Phase:
N/A
Details
Lead Sponsor:
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh