Esomeprazole in Treatment of Early Onset Preeclampsia (ESOPE Trial)
Status:
Completed
Trial end date:
2020-10-15
Target enrollment:
Participant gender:
Summary
Pre-eclampsia is one of the most serious complications of pregnancy affecting 3-8 % of
pregnancies worldwide. It is a multi-system disorder involving maternal vessels (causing
hypertension and endothelial dysfunction), the kidneys, the liver, the lungs, the
hematological system, the cardiovascular system and the feto-placental unit. In its most
severe form, it affects the brain, causing seizures (eclampsia), cerebro-vascular events and
even death.