Esomeprazole Treatment for Patients With Lymphocytic Gastritis

• Status: Unknown status
• Trial end date: 2009-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether treatment with esomeprazole alone is able to heal patients with lymphocytic gastritis

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Technische Universität Dresden
• Treatments: Esomeprazole

Criteria

Inclusion Criteria:

• Histologically proven lymphocytic gastritis (IEL > 25/100)

• Male or female aged 18 years or older

• Signed and written informed consent

Exclusion Criteria:

• Regular NSAID or aspirin intake

• Concomitant medication with antibiotics, bismuth subsalicylate, aminosalicylates

• Regular PPI therapy

• Treatment with ketoconazole or other CYP3A inhibitors

• previous surgery of the stomach

• known or suspected hypersensitivity to esomeprazole

• Malignant diseases

• Concomitant severe diseases

• Pregnancy or lactation

• Contraindication to take biopsies (Quick < 50%, PTT > 50 s, thrombocytes < 100.000/mm3)