Esomeprazole (NEXIUM) vs. Surgery

• Status: Completed
• Trial end date: 2009-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The study investigates the efficacy of long-term treatment of esomeprazole compared to anti-reflux surgery in the control of gastroesophageal reflux disease by assessing time to treatment failure.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: AstraZeneca
• Treatments: Esomeprazole

Criteria

Inclusion Criteria:

• Subjects considered suitable for surgical treatment and long-term management of esomeprazole.

• History of chronic reflux esophagitis or symptomatic GERD

Exclusion Criteria:

• History of esophageal, gastric, or duodenal surgery predicted to influence negatively on subsequent treatment within the study.

• Contraindication to the study drug.

• Pregnancy, lactating or of child-bearing potential.