Esmolol in Cardiac Surgery

• Status: Completed
• Trial end date: 2018-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This large randomized double-blind clinical trial (esmolol vs placebo) will enroll patients undergoing cardiac surgery to study the additive cardiac protection of this therapeutic strategy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Università Vita-Salute San Raffaele
• Treatments: Adrenergic beta-Antagonists; Esmolol

Criteria

Inclusion Criteria:

• end diastolic diameter >60 mm and/or an ejection fraction <50%

• written informed consent

• age >18 years

Exclusion Criteria:

• previous unusual response to esmolol

• inclusion in other randomized studies

• esmolol administration in the previous 30 days

• emergency operation