Esmolol Versus Dexmedetomidine During Intracranial Procedures
Status:
Unknown status
Trial end date:
2017-10-01
Target enrollment:
Participant gender:
Summary
Patients undergoing intracranial procedures may experience severe hypertension and
tachycardia due to intracranial hypertension and to increased release of adrenaline.
Preventing perioperative sympathetic activity is of great importance. A common technique is
using b-blockers like esmolol, which effectively block perioperative hemodynamic changes
during intracranial surgery. A2 agonists, like Dexmedetomidine-Dex are now being used as a
component of a balanced anesthesia during neurosurgical procedures. This study aimed to
evaluate whether esmolol or dex attenuates perioperative changes in patients undergoing
elective craniotomy with fast track neuroanesthesia.