Overview

Erythropoietin Effect on Ischemic_ Reperfusion Injury in Coronary Artery Bypass Graft Surgery

Status:
Completed
Trial end date:
2017-06-01
Target enrollment:
0
Participant gender:
All
Summary
The aim of this trail is to assess the safety and therapeutic effects of single EPO intervention in different times during coronary surgery in changes of inflammatory response.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Shahid Beheshti University of Medical Sciences
Collaborator:
Pooyesh Darou
Treatments:
Epoetin Alfa
Criteria
Inclusion Criteria:

- Revascularization requirement according to angiographic evidence

- Elective coronary artery bypass graft surgery

- First time coronary artery bypass graft surgery

- On-pump coronary artery bypass graft surgery

Exclusion Criteria:

- History of myocardial infarction in the past 3 months

- Previous myocardial trauma or major surgery in the past 3 months

- Cr>2mg/dl

- Receiving streptokinase or previous reperfusion treatments

- Erythropoietin intake in the recent 6 months

- Known thromboembolic disorder and malignant disease

- Uncontrolled hypertension

- Polycythemia

- Previous valvular surgery