Εffectiveness of Intrauterine Antibiotic Administration for Treatment of Chronic Endometritis

• Status: Recruiting
• Trial end date: 2023-01-31
• Target enrollment: 0
• Participant gender: Female

Summary

Chronic Endometritis (CE) is related to infertility and entails a challenging management. This study investigates the treatment of off-label intrauterine antibiotic infusion either separately or combined with oral antibiotic administration, and it assesses respective performance against the gold standard treatment of oral antibiotic adminstration. Data sourced herein reports on treatment efficiency, defined as a negative diagnosis for chronic endometritis.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Genesis Athens Clinic
• Collaborator: National and Kapodistrian University of Athens

Criteria

Inclusion Criteria:

• Positive diagnosis of CE following hysteroscopy and endometrial biopsy (positive diagnosis is required by both evaluations)

• Signed Informed Consent

• 18.5 < BMI < 30

Exclusion Criteria:

• Diagnosed endometriosis or other related Pelvic Inflammatory Disorder (PID)

• Current or previous cancer diagnosis

• Auto-immune or genetic disorders

• Menstrual cycle disorders