Epirubicin, Oxaliplatin and Fluorouracil (EOF) in Cancer of the Esophagus, Gastroesophageal Junction, or Stomach
Status:
Completed
Trial end date:
2015-01-23
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as epirubicin, oxaliplatin, fluorouracil, and
cisplatin, work in different ways to stop the growth of tumor cells, either by killing the
cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill
tumor cells. Giving chemotherapy before surgery may make the tumor smaller and reduce the
amount of normal tissue that needs to be removed. Giving chemotherapy and radiation therapy
after surgery may kill any tumor cells that remain after surgery.
PURPOSE: This phase II trial is studying how well giving combination chemotherapy, surgery,
and radiation therapy works in treating patients with locoregionally advanced cancer of the
esophagus, gastroesophageal junction, or stomach.