Epinephrine Infusion for Prophylaxis Against Maternal Hypotension After Spinal Anesthesia for Cesarean Delivery

• Status: Not yet recruiting
• Trial end date: 2023-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Subarachnoid block is the common route of anesthesia for cesarean delivery. Maternal hypotension after subarachnoid block is very common despite the vigorous methods for its prevention. Maternal hypotension is sometimes deleterious to the mother and the fetus; thus, it is highly recommended to use prophylactic vasopressors directly after the block and before the blood pressure drops. The aim of this work is to compare the maternal and neonatal effects of epinephrine and phenylephrine when used as prophylactic infusion after subarachnoid block for cesarean delivery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University
• Treatments: Epinephrine; Oxymetazoline; Phenylephrine

Criteria

Inclusion Criteria:

• full-term singleton pregnant women, admitted for elective cesarean delivery

• aged between 18 and 40 years

Exclusion Criteria:

• Patients with uncontrolled cardiac morbidities, hypertensive disorders of pregnancy

• Peripartum bleeding

• coagulation disorders

• Baseline systolic blood pressure (SBP) < 100 mmHg