In order to investigate how gut microbiota interventions are able to change gut microbiota
population and impact insulin resistance, 30 type2 diabetes volunteers with obesity will be
randomized to one of the three treatment groups: 1) probiotics arm, who will take a
Lactobacillus fermentum D3 in pills daily; 2) FMT arm, who will take a lyophilized fecal
microbiota transplant in pills; and 3) control group, who will take placebo pills. After 3
months, insulin resistance, glucose metabolism parameters, and gut microbiota variation will
be assessed.
Phase:
Early Phase 1
Details
Lead Sponsor:
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud