Epidural Neostigmine for Labor Pain

• Status: Completed
• Trial end date: 2013-11-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to see which dose of epidural neostigmine is the best additive to use with the numbing medication used in an epidural during labor.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Wake Forest School of Medicine; Wake Forest University
• Treatments: Bupivacaine; Fentanyl; Neostigmine

Criteria

Inclusion Criteria:

• Healthy pregnancy

• Term pregnancy ( > 37 weeks)

• Primiparous or multiparous

• Induction or spontaneous labor greater or = 18 years of age

• Cervical exam on entry Exclusion Criteria:

• Weight > 115 kg

• Non-English speaking

• IV analgesics within 60 minutes prior to epidural being administered

• Allergy to local anesthetics or neostigmine