Epidural Dexmedetomidine vs Nalbuphine for Labor Analgesia

• Status: Completed
• Trial end date: 2022-03-12
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is to compare epidural dexmedetomidine vs nalbuphine added to bupivacaine in labor analgesia and determine the privilege of one over the other and to compare the effect of both analgesics after delivery.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Dexmedetomidine; Nalbuphine

Criteria

Inclusion Criteria:

All the parturients should :

1. Be between 21 - 40 years old

2. ASA classification I- II

3. Para 1-2

4. Requesting analgesia

5. Have a normal birth canal

6. Be at the beginning of active phase of labor i.e. cervical dilatation of 4 cm with regular uterine contractions.

7. The fetus should be a single full-term fetus (37- 42 weeks of gestation) with normal head position, normal development.

Exclusion Criteria:

Parturients

1. Younger than 21 and older than 40 years old

2. With contraindication of regional anesthesia

3. With pre-existing neurological disease

4. With history of allergy to the study drugs

5. With cephalopelvic disproportion, fetal distress, amniotic fluid infection, placental insufficiency or scarred uterus