Overview

Epidural Catheter With or Without Adductor Canal Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty

Status:
Completed
Trial end date:
2017-01-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to further investigate the efficacy of adductor canal nerve blocks for pain management after total knee replacement. Specifically we are studying adductor canal nerve blocks in conjunction with epidural anesthesia, which is a combination that has not been extensively researched before. Our question is whether combining these modalities will enhance patient satisfaction after surgery and accelerate patients' readiness to discharge.
Phase:
N/A
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University of Chicago
Treatments:
Bupivacaine
Criteria
Inclusion Criteria:

- end stage degenerative joint disease

- enrolled for unilateral total knee arthroplasty at the University of Chicago

- age < 85

- ability to understand and willingness to sign a written informed consent

Exclusion Criteria:

- age > 85

- American Society of Anesthesiologists physical status > 3

- known hypersensitivity to lidocaine, bupivacaine, ropivacaine or other local
anesthetic agents

- Coagulopathy, specifically INR > 1.5, Platelets < 100, therapy with clopidogrel within
5 days prior to surgery, enoxaparin or fondaparinux within the last 24 hours prior to
surgery, patients with anti-phospholipid syndrome requiring aggressive anticoagulation
perioperatively

- History of alcohol or substance abuse (including strong opioids - morphine, oxycodone,
methadone, fentanyl, ketobemidone), taking > 50 mg morphine equivalent daily of
opioids

- Pre-existing femoral neuropathy or radiculopathy

- Patients with poor ability to communicate