Enzyme Suppletion in Exocrine Pancreatic Dysfunction
Status:
Completed
Trial end date:
2013-02-01
Target enrollment:
Participant gender:
Summary
Treatment of exocrine insufficiency (EPI) consists of pancreatic enzyme replacement according
to the fat intake. Prescribing a sufficient dose of pancreatic enzymes is mandatory for the
treatment to be effective. In addition, consultation of a specialized dietician is pivotal to
educate patients about the proper use of pancreatic enzymes. However, based on a recent
prospective survey in the Netherlands amongst chronic pancreatitis patients, it seems that
enzymes are underused and a dietician is seldom consulted. The aim of this study is to assess
if there is a difference in efficacy of pancreatic enzymes in a self-dosage regimen after
extensive patient-education in comparison to the standard treatment for patients with EPI.