The primary objective of this pilot study to evaluate the safety of low dose Entolimod in
normal, healthy, non-patient normals. This clinical trial in 40 normal humans compares a
single dose of 4 ug Td (2 ug of TT and 2 ug of diphtheria toxoid + 3000 ug of alum with or
without entolimod. Subjects will be randomized to: Td alone (n=15) and Td+ entolimod (n=25).
The investigators expect that Td + entolimod will double the anti-TT and anti-diphtheria AB
levels over Td alone.