Overview

Enteral Nutrition as Stress Ulcer Prophylaxis in Critically Ill Patients.

Status:
Completed
Trial end date:
2016-07-01
Target enrollment:
0
Participant gender:
All
Summary
study is to determine if proton pump inhibitors plus enteral nutrition is superior to enteral nutrition alone as a stress ulcer prophylaxis strategy in critically ill patients in terms of incidence of overt and significant GI bleeding related to stress gastropathy.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Mohamed Saad
Collaborators:
Abbott Nutrition
University of Louisville
Treatments:
Pantoprazole
Criteria
Inclusion Criteria:

- Age 18 years or older

- Admission to the medical ICU at University of Louisville Hospital or Jewish Hospital

- Expected need for mechanical ventilation > 48 hours

- No contraindication to EN within the first 24 hours after admission to the ICU

Exclusion Criteria:

- Evidence of active GI bleeding during current hospitalization prior to study entry

- Admission to ICU with primary diagnosis of burn injury

- Closed head injury or increased intracranial pressure

- Partial or complete gastrectomy

- Pregnancy or lactation