The purpose of this study is to investigate whether enoxaparin, minocycline, or both
medications in combination may help in recovery from acute stroke.
Enoxaparin (brand name Lovenox®) is a medication approved for use in humans to prevent and to
treat blood clots in deep veins in certain specific medical situations. Minocycline (brand
name Minocin®) is a tetracycline antibiotic approved to treat a number of bacterial
infections in humans. The investigators are studying these medications in acute human stroke
because they have each been separately shown to reduce the amount of injured brain tissue in
rats made to have acute ischemic stroke experimentally. In a human trial comparing
minocycline with placebo (a sugar pill) acute ischemic stroke patients who took minocycline
had better recovery after 1 week, 1 month and 3 months than patients who took placebo.
Phase:
N/A
Details
Lead Sponsor:
New York University School of Medicine NYU Langone Health