Enhancing the Efficiency of EMLA Cream in Palatal Anesthesia for Children

• Status: Completed
• Trial end date: 2021-09-27
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to Avoid traditional palatal local injections when extracting upper primary teeth through enhancing the efficiency of EMLA cream by using drug delivery systems (permeability enhancer (DMSO), oral patches and micro-needle patches) for palatine injection.

Group 1: Conventional local palatine injection (control group). Group 2: EMLA cream only. Group 3 :chemical permeability enhancer DMSO with EMLA cream. Group 4: Oral patches with EMLA Cream. Group 5: Micro-needle patches dissolved with EMLA Cream.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Damascus University
• Treatments: Lidocaine, Prilocaine Drug Combination

Criteria

Inclusion Criteria:

• no previous dental experience.

• Healthy children.

• Definitely positive or positive ratings of Frank scale

• Child did not receive any sedative or pain drugs during the last three.

• Presence of upper primary teeth, an indication for extraction

Exclusion Criteria:

• Presence of general diseases or health problems.

• Uncooperative children

• Children with congenital or idiopathic Methemoglobin

• Teeth with severe abscesses