Enfortumab Vedotin for the Treatment of Patients With Metastatic or Unresectable Squamous Cell Carcinoma of the Penis
Status:
Recruiting
Trial end date:
2026-11-01
Target enrollment:
Participant gender:
Summary
This phase II trial tests how well enfortumab vedotin works for treating patients with
squamous cell carcinoma of the penis that has spread to other places in the body (metastatic)
or cannot be removed by surgery (unresectable). Enfortumab vedotin is a monoclonal antibody,
enfortumab, linked to an anticancer drug called vedotin. It works by helping the immune
system to slow or stop the growth of tumor cells. Enfortumab attaches to a protein called
nectin-4 on tumor cells in a targeted way and delivers vedotin to kill them.