Endothelin Receptor Blockade in Acute ST-elevation Myocardial Infarction
Status:
Completed
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
Background and Objective: Acute coronary syndrome is characterized by compromised blood flow
at the epicardial and microvascular levels. The aim of the present study is to investigate
the effect of ET-receptor blockade by BQ-123 on myocardial perfusion and infarct size as an
adjunct to PCI-reperfusion therapy in patients with STEMI.
Patients are randomized to receive periinterventional intravenous BQ-123 or placebo.