Overview

Endothelial Protection in Post COVID-19 Patients With Sulodexide

Status:
Not yet recruiting
Trial end date:
2022-11-12
Target enrollment:
Participant gender:
Summary
This is a Prospective, multicenter, randomized (1:1, placebo use) trial with a parallel-group design to assess if the use of sulodexide influences serum levels of biomarkers for endothelial dysfunction on convalescent COVID-19 patients who suffered a moderate (or more severe) clinical presentation and have chronic comorbidities of high risk for endothelial dysfunction. The recruitment period is estimated at 6 months. The follow-up period of all participants will be 8 weeks. The participant will receive according to group allocation after randomization 1. study group: sulodexide oral dose of 250LRU capsule bid for 8 weeks. 2. control group: placebo oral dose of 1 capsule bid for 8 weeks. Participants in both groups will continue the standard of care recommended by national healthcare guidelines for each Country, including any concomitant medication indicated by their primary physician.
Phase:
Phase 3
Details
Lead Sponsor:
Centro Medico del Noroeste
Collaborator:
Alfasigma S.p.A.
Treatments:
Glucuronyl glucosamine glycan sulfate