Endothelial Function in a Sample Group of Patients From the ICARE Study
Status:
Completed
Trial end date:
2007-12-01
Target enrollment:
Participant gender:
Summary
The ICARE study, clinicaltrials.gov ID number: NCT00220831 and protocol number KL-2004, is
recruiting diabetic patients with haptoglobin phenotype 2-2, which are randomised to either
Vitamin E 400IU per day or placebo. Patients will be followed for 4 years for the major
cardiovascular complications of diabetes, acute myocardial infarction (MI), stroke and
cardiovascular mortality (see ICARE protocol). The EFI study, Endothelial Function in ICARE
will recruit a sample group of 50 patients from the ICARE cohort. These patients will
complete all requirements by ICARE protocol and in addition will be tested for endothelial
function by a non-invasive method of flow mediated dilatation (FMD).
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Technion, Israel Institute of Technology
Collaborators:
Clalit Health Services Rambam Health Care Campus
Treatments:
alpha-Tocopherol Tocopherols Tocotrienols Vitamin E Vitamins