Endothelial Function in Lower Extremity Bypass Grafts

• Status: Completed
• Trial end date: 2009-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will determine whether or not saphenous vein [arterial] bypass grafts in the leg relax in response to increases in blood flow.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Brigham and Women's Hospital
• Treatments: omega-N-Methylarginine

Criteria

Inclusion Criteria:

• Adults who have undergone femoral artery to above-knee popliteal artery saphenous vein bypass grafts

Exclusion Criteria:

• Amputation beyond the toes

• Critical limb ischemia defined as rest pain, non-healing ulceration or gangrene

• Pregnancy