Endophenotype for Alcohol Misuse in Healthy Minority Populations
Status:
Completed
Trial end date:
2008-05-01
Target enrollment:
Participant gender:
Summary
The purpose of the study is to understand the relationship between what an individual
inherited from their family (genetics), how they respond and feel after drinking alcohol, and
how they respond to pre-treatment with naltrexone, a medication that blocks some of the
effects of alcohol and is approved for the treatment of alcoholism. The investigators are
conducting this study on those of African descent because there is almost no research focused
on this group and the association with genetics. The investigators seek to enroll 40 people
in the study. Participation will consist of 4 different alcohol challenge sessions in a cross
over design. Each session will be separated by at least 10 days. In total, there will be four
challenge sessions.