Endometriosis and Microvascular Dysfunction; Simvastatin and Duavee
Status:
Not yet recruiting
Trial end date:
2026-12-01
Target enrollment:
Participant gender:
Summary
Purpose: To determine the effects of SERM and simvastatin interventions on endothelial
dysfunction in women with endometriosis.
Hypothesis: Treatment with the SERM (bazedoxifene + conjugated estrogen) or with simvastatin
will decrease systemic inflammation and improve specific measures of cardiovascular function
including endothelium-dependent vasodilation.