Overview

Emricasan, an Oral Caspase Inhibitor, in Subjects With Non-Alcoholic Steatohepatitis (NASH) Cirrhosis and Severe Portal Hypertension

Status:
Completed

Trial end date:
2019-05-07

Target enrollment:

Participant gender:

Summary

This is a multicenter, randomized, double-blind, placebo-controlled trial involving subjects with NASH cirrhosis and severe portal hypertension (defined as HVPG ≥12 mmHg as determined by the central reader assigned to this study). Upon successful screening, subjects will be randomized to receive either emricasan 50 mg BID, 25 mg BID, or 5 mg BID or matching placebo BID.

Phase:

Phase 2

Details

Lead Sponsor:

Conatus Pharmaceuticals Inc.

Treatments:

Caspase Inhibitors