Emergency Department-Initiated Medications for Alcohol Use Disorder
Status:
Not yet recruiting
Trial end date:
2027-04-01
Target enrollment:
Participant gender:
Summary
The proposed study will be the first randomized clinical trial to evaluate a comprehensive
Emergency Department (ED)-based intervention for moderate to severe Alcohol Use Disorder
(AUD) combining Screening, Brief Intervention and Referral to Treatment (SBIRT) with
ED-initiated medications for treatment of alcohol use disorder (MAUD).
The primary objective of this phase 3 study is to evaluate for differences in treatment
engagement 30 days after ED visit between emergency department patients with moderate to
severe alcohol use disorder (AUD) who are randomized to initiate medications for the
treatment for AUD in the ED in addition to receiving a brief intervention and referral to
ongoing treatment, which all participants will receive.
The secondary objective of this study is to evaluate the difference in reduction of heavy
drinking days between the two ED treatment models during the 30 days post ED visit.
Phase:
Phase 3
Details
Lead Sponsor:
Yale University
Collaborator:
National Institute on Alcohol Abuse and Alcoholism (NIAAA)