Emergence Agitation Between Sevoflurane and Desflurane in Pediatric
Status:
Completed
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
Sevoflurane is the volatile anesthetic agent of choice in pediatric surgery. Nevertheless,
sevoflurane anesthesia had the high incidence of emergence delirium compared to halothane and
isoflurane.Bortone L et al.reported isoflurane for maintenance decreased incidence of
emergence agitation compared to sevoflurane in unpremedicated preschool children under
elective subumbilical surgery (32% versus 52% respectively). Desflurane is the new volatile
anesthetic agent which provides faster recovery compared to sevoflurane.Valley et al.reported
no significant differences between sevoflurane or desflurane anesthesia in children in term
of the serious airway complication such as laryngospasm or desaturation excepted the number
of coughing episodes were more frequent in the desflurane compared to sevoflurane (36 versus
18).Mayer J et al. reported sevoflurane had severity of Pediatric Anesthesia Emergence
Delirium (PAED) scale higher than desflurane in ear, nose, throat inpatient surgery in
children (12(2-20) versus 6(0-15) respectively) with no reported of incidence of emergence
agitation between those two. Therefore, the investigators would like to compare the incidence
of emergence agitation, recovery profile and respiratory events between desflurane and
sevoflurane anesthesia in pediatric ambulatory urologic surgery under general anesthesia and
combined with regional anesthesia.