Overview

Emapalumab Prevention of CAR-T Cell Associated Toxicities

Status:
RECRUITING
Trial end date:
2027-08-01
Target enrollment:
Participant gender:
Summary
This research study involves assessing the impact of emapalumab as preventative management of CAR-T related cytokine release syndrome in participants with Non-Hodgkin's lymphoma (NHL). The research study involves the following study interventions: * Fludarabine and cyclophosphamide (Lymphodepleting Chemotherapy) * Axicabtagene Ciloleucel * Emapalumab
Phase:
PHASE2
Details
Lead Sponsor:
Marcela V. Maus, M.D.,Ph.D.
Collaborator:
Swedish Orphan Biovitrum
Treatments:
Antibodies, Monoclonal
axicabtagene ciloleucel
Cyclophosphamide
Emapalumab
fludarabine phosphate