Elucidation of Acid-Induced Pulmonary Inflammation
Status:
Terminated
Trial end date:
2009-04-01
Target enrollment:
Participant gender:
Summary
This study will evaluate how heartburn may lead to different types of inflammation in one's
airways. Additionally, the study will determine whether aggressive treatment of heartburn
results in improvement in both symptoms of heartburn and asthma but also in documented
improvement in airway inflammation as determined by biopsy. The results of this study will be
important in directing future research into the relationship between heartburn and asthma and
may provide a clue whether certain subtypes of asthma may be caused primarily by
gastroesophageal reflux (GER).