Overview

Electronic Cigarette-derived Oxidants and Cardiopulmonary Effects

Status:
ACTIVE_NOT_RECRUITING
Trial end date:
2026-06-30
Target enrollment:
Participant gender:
Summary
This is a pilot study on the impact of switching from cigarettes to Electronic Cigarettes (EC) on disease-related clinical symptoms and biomarkers of harm in smokers with preexisting Chronic Obstructive Pulmonary Disease (COPD). The researchers hypothesize that the smokers who switch to EC completely or significantly will experience reduced COPD symptoms, risks of exacerbations, and decreased levels of oxidative stress and inflammation.
Phase:
EARLY_PHASE1
Details
Lead Sponsor:
Milton S. Hershey Medical Center
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)