Efficacy of a Triptan in the Treatment of Hostility and Aggression Among Convicts With a Psychiatric Treatment Order
Status:
Terminated
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
In a double blind randomized clinical trial with cross-over design, treatment using
naratriptan will be compared to placebo within a group of 30 convicts with psychiatric
disorders such as psychosis or psychopathy with repeated aggressive outbursts resistant to
conventional psychopharmacologic and other psychotherapeutic treatment. Hypothesis is that
addition of naratriptan to the individual treatment regime reduces aggression -and improves
general outcome- as compared to addition of placebo and is well tolerated in this group and
under these conditions.