Overview

Efficacy of Zylet vs. Lotemax for the Treatment of Ocular Surface Inflammation/MGD/Blepharitis

Status:
Completed
Trial end date:
2017-06-01
Target enrollment:
Participant gender:
Summary
This is a Phase IV, single site, randomized, double masked, parallel control clinical trial of 60 subjects to investigate the variance of efficacy between Lotemax® and Zylet® for treatment of ocular surface inflammation due to meibomian gland dysfunction (MGD). Efficacy will be measured by in-vivo confocal microscopy, corneal fluorescein staining, grading of meibomian gland dysfunction and validated ocular symptom assessment questionnaire.
Phase:
Phase 4
Details
Lead Sponsor:
Massachusetts Eye and Ear Infirmary
Collaborator:
Bausch & Lomb Incorporated
Treatments:
Loteprednol Etabonate
Lubricant Eye Drops
Ophthalmic Solutions
Tetrahydrozoline
Tobramycin