Efficacy of Ultrasound Guided PIFB Versus Lidocaine Infusion on Postoperative Pain After Thoracotomy

• Status: Recruiting
• Trial end date: 2024-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Chronic pain is a common complication after cardiothoracic surgery. The prevalence of post-thoracotomy pain syndrome (PTPS) ranges from 33% to 91%. Exact pathogenetic mechanisms for developing chronic pain after thoracotomy are unknown. Apart from intraoperative nerve damage and subsequent postoperative neuropathic pain, operation techniques, age, sex, pre-existing pain, genetic and psychosocial factors, severe postoperative pain, and analgesic management are suspected to have an impact on the development of PTPS .

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Beni-Suef University
• Treatments: Bupivacaine; Lidocaine

Criteria

Inclusion Criteria:

1. age between 18 and 75 years.

2. patient scheduled to undergo elective on-pump cardiac surgery with sternotomy.

3. American Society of Anesthesiologists classification of physical status < IV.

Exclusion Criteria:

1. emergency surgery.

2. off-pump surgery.

3. redo surgery.

4. ejection fraction less than 35%.

5. refusal of the patient.

6. known hypersensitivity to LA.

7. chronic opioid use or chronic pain patient.

8. psychiatric problems or communication difficulties.

9. liver insufficiency (defined as a serum bilirubin ≥ 34 μmol/l, albumin ≤ 35 g/dl, INR ≥ 1.7).

10. renal insufficiency (defined as a glomerular filtration rate < 44 ml/min).

11. obstructive sleep apnea syndrom.

12. coexisting hematologic disorders.

13. pregnancy or breastfeeding.