Efficacy of Treatment With Berberine to Maintain Remission in Ulcerative Colitis
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The research aim to find out whether berberine can reduce the annual recurrence rate of
ulcerative colitis in remission.
A total of 238 patients with ulcerative colitis in remission will be randomly divided into
two groups.One will receive regular treatment,and the other group will receive extra oral
berberine 300 mg three times daily for a year.
The end of the study for every patient is disease recurrence(Mayo Clinic score of 3 points or
more ).
The primary analysis is annual recurrence rate, and both endoscopy and Mayo Clinic disease
activity index scores at the baseline and final assessments.