Overview

Efficacy of Tetracaine/Oxymetazoline Nasal Spray for Endodontic Treatment

Status:
Withdrawn
Trial end date:
2019-07-01
Target enrollment:
Participant gender:
Summary
Purpose: To evaluate anesthetic efficacy and overall patient experience with use of Kovanaze tetracaine/oxymetazoline nasal spray for root canal treatment of vital premolar and anterior teeth needing root canal treatment. Participants: 30 adult patients with a vital upper anterior or premolar tooth (#4-13) with a diagnosis indicating need root canal treatment and who are seeking treatment in the UNC Chapel Hill School of Dentistry. Procedures (methods): Qualifying patients will be anesthetized with tetracaine/oxymetazoline nasal spray anesthetic in order to facilitate completion of their clinically required, standard of care root canal treatment. Research procedures include blood pressure monitoring and pain assessment using a visual analogue pain scale.
Phase:
Phase 4
Details
Lead Sponsor:
University of North Carolina, Chapel Hill
Treatments:
Oxymetazoline
Phenylephrine
Tetracaine