Efficacy of Tazarotene in Treatment of Verruca Plana
Status:
Not yet recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
Verruca plana is a common skin infection with worldwide distribution. Approximately 10% of
general population is infected with flat warts and it represents up to 18 % of the patients
seeking treatment for warts. Verruca plana is not merely an infectious disease but also
affects the quality of patients' life. Verruca plana causes major cosmetic and social
concerns. Lesions' persistence and recurrence cause frustrations and psychological distress
which motivate patients to seek different treatment strategies. Verruca plana commonly
affects the school aged children which augments its effect on the psychological and social
development of children with stigmatization and bullying are great risks. The available
treatment strategies neither ensured complete clearance of the disease nor were free of side
effects. Frequently used physical removal methods are operator dependent and commonly lead to
irritation, local inflammation, scars, dyspigmentation, and disfigurement. In this study we
evaluate the efficacy and the safety of tazarotene gel 0.1% in the treatment of verruca plana
compared to imiquimod or 5-fluorouracil