Efficacy of Spinal Oxytocin in Healthy Volunteers

• Status: Recruiting
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the effect of intrathecal oxytocin on areas and intensity of hyperalgesia and allodynia induced by topical capsaicin.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: James C. Eisenach, M.D.; Wake Forest University Health Sciences
• Treatments: Oxytocin

Criteria

Inclusion Criteria:

• healthy

• weight < 240 pounds

• American Society of Anesthesiology Category 1 or 2

Exclusion Criteria:

• allergy to oxytocin or lidocaine

• allergy to chilli peppers

• Females: active gynecological disease such as uterine fibroids or ongoing bleeding

• Pregnancy or currently breastfeeding

• Females that have delivered a baby within 2 years of study

• Taking prescription medications (exception: oral birth control medication)