Efficacy of Saline Injection Therapy in Atrophic Acne Scars

• Status: Completed
• Trial end date: 2019-07-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study was to determine the efficacy of saline injection in post-acne atrophic scars on face. All patients with mild, moderate & severe post-acne atrophic scars, above age of 15 years without any co-morbid conditions were included in the study. After giving local anesthesia, the isotonic saline solution has been administered intra- and sub-dermally in post-acne atrophic scars on face. The sessions were done weekly, for 12 weeks. The results were assessed by the photographs, sharquie scoring system & Dermatology Life Quality Index score at the start and at the end of the treatment. SPSS 23 was used to analyze the data. The analysis of data showed that the response of saline injection was significant in mild and moderate scars, without any significant side effects.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Jinnah Postgraduate Medical Centre

Criteria

Inclusion Criteria:

• Minimum age 15years

• Maximum age 35 years

• Both males and females with mild, moderate and severe post-acne atrophic scars on face.

Exclusion Criteria:

• Hypertension

• Cardiovascular disorders

• Pregnancy

• Lactation

• Hypersensitivity to lidocaine.